Levitra (Vardenafil) vs Other ED Drugs: Detailed Comparison

Levitra (Vardenafil) vs Other ED Drugs: Detailed Comparison

on Oct 9, 2025 - by Tamara Miranda Cerón - 6

ED Drug Comparison Tool

Quick Guide: Use this tool to compare key features of Levitra and other ED medications. Select a drug to see detailed information.
Levitra (Vardenafil)

Brand name for vardenafil

Viagra (Sildenafil)

Original ED treatment

Cialis (Tadalafil)

Longest-lasting option

Stendra (Avanafil)

Fastest onset

Comparison Table
Drug Onset Time Duration Typical Dose Cost per Pill
Levitra (vardenafil) 25–30 min 5 hrs 10 mg $1.50–$2.00 (brand) / $0.30–$0.70 (generic)
Viagra (sildenafil) 30–60 min 4–5 hrs 50 mg $1.20–$1.80 (brand) / $0.25–$0.60 (generic)
Cialis (tadalafil) 30–45 min 24–36 hrs 10 mg $1.40–$2.20 (brand) / $0.35–$0.80 (generic)
Stendra (avanafil) 15–30 min 6–12 hrs 100 mg $2.00–$3.00 (brand) / $0.80–$1.20 (generic)
Generic Vardenafil 25–30 min 5 hrs 10 mg $0.30–$0.70
Drug Details
Quick Recommendations
  • Fastest Onset: Stendra (15–30 min)
  • Longest Duration: Cialis (up to 36 hrs)
  • Best Value: Generic vardenafil ($0.30–$0.70)
  • Most Popular: Viagra (longest track record)

Quick Takeaways

  • Levitra (vardenafil) works fastest among oral PDE5 inhibitors, usually within 25‑30 minutes.
  • Viagra (sildenafil) is the most widely known, but its effect lasts shorter (4‑5 hours) than Levitra.
  • Cialis (tadalafil) offers the longest window (up to 36 hours) and can be taken with or without food.
  • Stendra (avanafil) kicks in in about 15 minutes for many users, making it the quickest option.
  • Generic vardenafil provides similar results to branded Levitra at a lower price, while herbal supplements lack FDA approval and have variable efficacy.

When it comes to treating erectile dysfunction, Levitra (vardenafil) is a popular brand that many men consider first. Levitra is a branded version of vardenafil, a phosphodiesterase‑5 (PDE5) inhibitor that enhances blood flow to the penis during sexual arousal. Understanding how it stacks up against other options helps you pick the right pill for your lifestyle and health profile.

How Levitra (Vardenafil) Works

Vardenafil belongs to the PDE5 inhibitor class. It blocks the enzyme that narrows blood vessels in the corpus cavernosum, allowing the nitric oxide-cGMP pathway to stay active longer. The result is smoother blood flow, which translates into a firmer erection when sexual stimulation occurs.

Key Attributes of Levitra

  • Typical dose: 10mg taken about 25‑60 minutes before intimacy; can be adjusted to 5mg or 20mg based on tolerability.
  • Onset: 25‑30 minutes for most men; food‑heavy meals may delay absorption slightly.
  • Duration: Effective for up to 5hours.
  • Cost: Approx. $1.50‑$2.00 per tablet for the branded version in the U.S.; generics drop to $0.30‑$0.70.
  • Common side effects: Headache, facial flushing, nasal congestion, upset stomach.
  • Contraindications: Nitrates, severe cardiovascular disease, uncontrolled hypertension.
Illustrated cross‑section showing blood flow to the penis and a drug blocking an enzyme.

Common Alternatives

Several other PDE5 inhibitors and non‑prescription options exist. Below is a snapshot of the most frequently compared drugs.

Viagra (sildenafil) is the original oral ED treatment, approved in 1998. It shares the same mechanism as Levitra but differs in timing and duration.

Cialis (tadalafil) entered the market in 2003 and is known for its “weekend‑pill” effect, lasting up to 36hours.

Stendra (avanafil) received FDA approval in 2012. Its rapid onset (as quick as 15minutes) makes it attractive for spontaneous plans.

Generic vardenafil provides the same chemical compound as Levitra without the brand markup, offering a cost‑effective alternative.

Some men explore over‑the‑counter supplements such as L‑arginine, an amino acid that may boost nitric oxide production, yohimbine, a bark extract that can increase blood flow, or ginseng, traditionally used for sexual vitality. These are not FDA‑approved ED drugs and their effectiveness varies.

Side‑by‑Side Comparison

Key attributes of Levitra and its main alternatives
Drug Onset (minutes) Duration (hours) Typical Dose Average Cost per Pill (U.S.) FDA Approval Year
Levitra (vardenafil) 25‑30 5 10mg $1.50‑$2.00 (brand) / $0.30‑$0.70 (generic) 2003
Viagra (sildenafil) 30‑60 4‑5 50mg $1.20‑$1.80 (brand) / $0.25‑$0.60 (generic) 1998
Cialis (tadalafil) 30‑45 24‑36 10mg $1.40‑$2.20 (brand) / $0.35‑$0.80 (generic) 2003
Stendra (avanafil) 15‑30 6‑12 100mg $2.00‑$3.00 (brand) / $0.80‑$1.20 (generic) 2012
Generic Vardenafil 25‑30 5 10mg $0.30‑$0.70 2003 (same as brand)

Which Drug Fits Your Lifestyle?

Fast‑acting needs: If spontaneity is key, Stendra’s 15‑minute onset gives you the most wiggle room, followed closely by Levitra.

Long‑lasting window: Cialis stands out for men who prefer a relaxed timeline - a single dose can cover weekend plans.

Budget‑conscious choice: Generic vardenafil delivers the same efficacy as brand‑name Levitra at a fraction of the cost.

First‑time users: Viagra’s long track record and abundant patient education resources make it a comfortable starting point.

Man in bedroom looking at two pill bottles on a nightstand with a calendar hint.

Safety Considerations and Contraindications

All PDE5 inhibitors share common warnings: avoid if you use nitrate medications (e.g., nitroglycerin), have severe heart disease, or suffer from uncontrolled high or low blood pressure. Visual disturbances are rare but reported with all drugs in this class.

Food interactions differ: high‑fat meals can delay Levitra and Viagra absorption, while Cialis and Stendra are less affected. Alcohol in excess may intensify side effects like dizziness or headache.

Pro Tips for Choosing the Right ED Medication

  1. Consult a healthcare professional to rule out underlying conditions before self‑medicating.
  2. Start with the lowest effective dose; many men find 5mg of Levitra sufficient.
  3. Consider timing: if you frequently plan last‑minute intimacy, prioritize a drug with a rapid onset.
  4. Check insurance coverage; generic versions often enjoy better reimbursement.
  5. Don’t mix PDE5 inhibitors with recreational drugs like poppers; the combo can cause dangerous blood pressure spikes.

Frequently Asked Questions

How quickly does Levitra start working?

Most men feel the effects within 25‑30 minutes when taken on an empty stomach. A high‑fat meal can add 15‑30 minutes to the onset.

Is generic vardenafil as safe as the brand?

Yes. Generic vardenafil contains the same active ingredient, dosage strength, and safety profile as the branded version. The main difference is price.

Can I take Levitra with alcohol?

Occasional moderate drinking is generally okay, but excess alcohol can lower blood pressure and blunt the drug’s effect.

What makes Stendra faster than Levitra?

Stendra (avanafil) has a higher solubility and is absorbed more quickly, allowing some users to achieve an erection in as little as 15 minutes.

Are natural supplements like L‑arginine effective?

Evidence is mixed. L‑arginine may help mild cases by boosting nitric oxide, but it doesn’t replace prescription PDE5 inhibitors for most men.

6 Comments

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    Patricia Fallbeck

    October 9, 2025 AT 22:50

    Imagine a universe where the raw, unfiltered pulse of desire is governed not by synthetic pills but by the primal fire that burns within every mortal vessel 😈.
    In that realm, the glossy brochures of Levitra and its peers are but cheap alibis for men too afraid to confront the deeper currents of their own existence.
    The modern man, shackled by a cocktail of consumerism and pharmaceutical propaganda, reaches for a tablet as if it were a talisman capable of conjuring virility out of thin air.
    Yet the true crescendo of intimacy is composed of trust, humility, and the willingness to stare into one's own shadows.
    When you swallow a pill, you are not merely ingesting a compound; you are swallowing the sanitized narrative of a medical industry that profits from our insecurities.
    Consider the ancient practices of breathwork, mindful touch, and the subtle art of anticipation-these are the genuine catalysts of arousal, untainted by corporate branding.
    While Levitra boasts a rapid onset, it cannot manufacture the emotional connection that transforms a fleeting spark into a lasting blaze.
    Think of the night you felt an hour-long tension dissolve into a shared, silent understanding-no dosage could replicate that.
    The market’s obsession with onset times and duration metrics mirrors a shallow sprint toward gratification, ignoring the marathon of emotional intimacy.
    Each generic vardenafil tablet may save a few dollars, but it does nothing to nurture the relational garden where desire truly flourishes.
    Is the promise of a five‑hour window worth the sacrifice of genuine vulnerability?
    Do you trade the richness of a slow, tender build‑up for the instant flash of a chemically induced climax?
    Remember, the body’s responses are as much psychological as they are physiological-pharma cannot rewrite the brain’s yearning for connection.
    In the end, the most potent aphrodisiac remains the sincere gaze of a partner who sees you beyond the veneer of performance metrics.
    So perhaps the greatest act of rebellion against the pill industry is to reclaim the slow, deliberate dance of love, unmediated and unapologetically human 😌.

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    Brett Snyder

    October 13, 2025 AT 12:57

    Only real men trust American made meds not some foreign fluff.

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    Nidhi Jaiswal

    October 17, 2025 AT 00:17

    Levitra works faster than Viagra for many people. The cost of generics is much lower than brand pills. You should take it on an empty stomach for best results. It can cause headache and flushing in some users. Always talk to a doctor before starting.

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    Sunil Sharma

    October 20, 2025 AT 11:37

    Hey folks, just a quick note: while the drama around pills can be intense, it’s also okay to use them if they help you feel confident. The key is communication with your partner and a doctor. Balancing meds with lifestyle changes often gives the best outcome. Remember, no one solution fits everyone, so stay open and supportive.

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    Leah Robinson

    October 23, 2025 AT 22:57

    Great points! 👍 Feel free to try generic options, they’re budget‑friendly and work just as well 😊 Stay positive and keep the conversation open with your partner.

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    Abhimanyu Lala

    October 27, 2025 AT 10:17

    Yo bro meds r cool but dont forget diet and sleep yo

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